adrenal hyperplasia
Definition
abnormal enlargement or overgrowth of adrenal gland tissue
Clinical context
A 32-year-old woman presents with hypertension, muscle weakness, and irregular menstrual cycles. Imaging reveals bilateral adrenal enlargement. Laboratory studies show elevated cortisol levels with suppressed ACTH. The patient's symptoms are most likely due to bilateral adrenal hyperplasia causing Cushing's syndrome.
Mnemonic
ADD-UP for adrenal hyperplasia: Abnormal, Dilated, Destructive, Unilateral, Overgrowth, Unilateral