Etymed

diabetic ketoacidosis

diabet ic keto acid osis

Definition

A serious complication of diabetes characterized by high blood glucose levels, ketone production, and metabolic acidosis

Clinical context

A 24-year-old with type 1 diabetes presents to the emergency department with nausea, vomiting, and abdominal pain for the past 12 hours. His blood glucose is 450 mg/dL, and his arterial blood gas shows a pH of 7.20 with elevated ketones. He appears dehydrated and lethargic. His recent insulin dose was skipped due to illness. This patient has diabetic ketoacidosis requiring urgent treatment with IV fluids and insulin.

Mnemonic

SICK DIABETES: Severe, Insulin deficiency, Dehydration, Ketosis, Acidosis, Elevated glucose

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