gigantism
Definition
A medical condition characterized by excessive growth and development, typically resulting from overproduction of growth hormone
Clinical context
A 28-year-old man presents to the endocrinology clinic with progressive enlargement of his hands, feet, and facial features over the past 3 years. He reports increased appetite, joint pain, and recently developed coarse facial features. His vital signs are normal, but physical examination reveals enlarged hands and feet with thickened skin. Laboratory studies show elevated growth hormone levels. Which condition is most likely causing these symptoms?
Mnemonic
GIGANTISM = Growth Hormone Overproduction in Children = Gigantism, Growth Hormone in Adults = Acromegaly