Etymed
hemolytic anemia
Definition
A condition characterized by the destruction of red blood cells (hemolysis) leading to a deficiency of healthy red blood cells in the circulation
Clinical context
A 28-year-old female presents with fatigue, shortness of breath, and yellowing of the eyes and skin. Laboratory studies show decreased hemoglobin, elevated bilirubin, and increased reticulocyte count. The patient's peripheral blood smear reveals schistocytes. Which of the following conditions best explains her symptoms? Hemolytic anemia is characterized by the premature destruction of red blood cells, leading to compensatory increased production by the bone marrow.
Mnemonic
HEMOLYSIS: Hemolysis, Edema, Mucosal bleeding, Overwhelming infection, Lactic acidosis, Icterus, Yellowness, Spleen enlargement, Hemoglobinuria, Anemia, Nausea, Oliguria