Etymed
hepatocellular carcinoma
Definition
A malignant tumor arising from liver cells (hepatocytes) characterized by uncontrolled growth and potential for metastasis
Clinical context
A 58-year-old man with a history of chronic hepatitis B presents with abdominal pain and weight loss over several months. Physical examination reveals an enlarged, firm liver edge. Laboratory studies show elevated alpha-fetoprotein levels. Imaging studies demonstrate a large mass in the right lobe of the liver. Biopsy confirms the diagnosis of hepatocellular carcinoma. This patient's condition is often associated with underlying liver cirrhosis and chronic viral hepatitis.
Mnemonic
HEPATIC cancer - HEPATOCYTE origin with AFP elevation
These morphemes also unlock…
- hepat/o — liver
- cellul/o — small cell (from cella, small room)
- -ar — pertaining to
- carcin/o — cancer
- -oma — tumor; mass