Etymed
hepatorenal syndrome
Definition
A condition characterized by the simultaneous dysfunction of both liver and kidney function, often seen in advanced liver disease
Clinical context
A 58-year-old man with cirrhosis presents to the emergency department with worsening confusion and decreased urine output. His serum creatinine has risen from 1.2 to 3.8 mg/dL over the past 3 days, and he has developed ascites that is refractory to diuretic therapy. His hepatorenal syndrome is likely precipitated by spontaneous bacterial peritonitis. He requires urgent evaluation for liver transplantation.
Mnemonic
HEPATIC kidney failure - HRS occurs in advanced liver disease with renal dysfunction