Etymed

hydatidiform mole

hydatid/o form/o mole

Definition

A benign trophoblastic tumor characterized by the presence of hydropic villi and abnormal proliferation of trophoblastic cells, resembling a bunch of grapes

Clinical context

A 35-year-old woman presents with vaginal bleeding and severe nausea at 12 weeks of gestation. Ultrasound reveals a characteristic 'snowstorm' appearance with no fetal heart tones, and her beta-hCG levels are dramatically elevated. The diagnosis of hydatidiform mole is confirmed by the presence of hydropic villi on histopathology.

Mnemonic

Look for the grapes - hydatidiform mole looks like a bunch of grapes on ultrasound

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