Etymed
hypercortisolism
Definition
A pathological condition characterized by excessive levels of cortisol in the blood, often due to adrenal gland dysfunction or prolonged stress
Clinical context
A 45-year-old woman presents with weight gain, particularly around her midsection and face, along with purple striae on her abdomen. She has been experiencing severe fatigue and mood changes for several months. Physical examination reveals elevated blood pressure and glucose levels. Laboratory tests show significantly elevated cortisol levels with failure to suppress cortisol with dexamethasone challenge.
Mnemonic
HYPERCORTISOLISM - Happy Young Women Experience Rapid Obesity, Muscle Weakness, and Infections