Etymed
hypocortisolism
Definition
A pathological condition characterized by insufficient production or secretion of cortisol by the adrenal cortex
Clinical context
A 34-year-old woman presents with profound fatigue, weight loss, and hypotension lasting several weeks. She has darkened skin pigmentation and low blood glucose levels. Laboratory studies reveal decreased cortisol levels and elevated ACTH. She is diagnosed with Addison's disease secondary to autoimmune destruction of the adrenal cortex.
Mnemonic
Addison's disease = 'Addison's disease' = 'Add' (adrenal) + 'ison' (hormone deficiency) + 'disease' = 'Adrenal insufficiency' = 'Hypo' (low) + 'cortisol' = 'Hypocortisolism'
These morphemes also unlock…
- hypo- — below; deficient
- cortisol/o — cortisol
- -ism — condition; state