Etymed

interstitial pneumonitis

inter- stiti/o -al pneumon/o -itis

Definition

Inflammation of the tissue between the air sacs (alveoli) in the lungs, typically affecting the interstitial spaces

Clinical context

A 65-year-old former coal miner presents with progressive dyspnea and dry cough over several months. Chest X-ray shows bilateral reticular opacities with honeycombing patterns. Pulmonary function tests reveal restrictive lung disease with reduced DLCO. These findings are consistent with interstitial pneumonitis affecting the lung interstitium.

Mnemonic

INFLAME interstitial spaces - INterstitial Lung disease with ALVEOLI inflammation

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