Etymed

lymphoblastic leukemia

lymph/o blast/o -ic leuk/o -emia

Definition

A type of leukemia characterized by the presence of immature lymphoblasts in the blood and bone marrow

Clinical context

A 12-year-old boy presents with fatigue, pallor, and frequent infections. Physical examination reveals hepatosplenomegaly and generalized lymphadenopathy. Laboratory studies show pancytopenia with 35% lymphoblasts in the peripheral blood smear. Bone marrow biopsy demonstrates hypercellular marrow with extensive infiltration by immature lymphoblasts.

Mnemonic

Lymphoblastic leukemia = Lymphoblasts + Blast crisis in blood and bone marrow

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