What does macrocytic anemia mean?

macrocytic anemia

macro- cyt/o -ic an- -emia

Definition

A type of anemia characterized by the presence of large, immature red blood cells (macrocytes) in the blood

Clinical context

A 65-year-old patient presents with fatigue and weakness. Laboratory results show large, immature red blood cells on peripheral smear with a mean corpuscular volume of 115 fL. The patient has a history of heavy alcohol use and takes methotrexate for rheumatoid arthritis.

Mnemonic

MACROCYTIC ANEMIA - MALT, METHOTREXATE, ALCOHOL, B12/12 DEFICIENCY

These morphemes also unlock…

macro- — large
cyt/o — cell
-ic — pertaining to
an- — without
-emia — blood condition

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