Etymed
mastocytosis
Definition
An abnormal condition characterized by an increased number of mast cells
Clinical context
A 35-year-old man presents with pruritus, flushing, and abdominal pain after eating certain foods. On examination, he has multiple brownish skin lesions. Laboratory studies reveal elevated serum tryptase levels and bone marrow biopsy shows increased mast cells. His symptoms are triggered by physical exertion and certain medications.
Mnemonic
Mast cells are like MASTers of inflammation, causing flushing and pruritus when activated
These morphemes also unlock…
- mast- — well-fed (referring to mast cells, from German Mastzellen)
- cyt/o — cell
- -osis — abnormal condition