Etymed

metabolic syndrome

metabol- -ic syndrome

Definition

A cluster of conditions that occur together, increasing risk of heart disease, stroke, and type 2 diabetes

Clinical context

A 45-year-old obese patient presents with elevated blood pressure, impaired glucose tolerance, and dyslipidemia. The combination of these metabolic abnormalities significantly increases their risk for cardiovascular events and diabetes. This constellation of findings represents the classic metabolic syndrome.

Mnemonic

METABOLIC: M - Metabolic dysfunction, E - Elevated BP, T - Triglycerides, A - Abdominal obesity, B - Beta-cell dysfunction, O - Oxidative stress, L - Lipid abnormalities, I - Insulin resistance, C - Cardiovascular risk, T - Target organ damage

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