Etymed
myelodysplasia
Definition
A condition characterized by ineffective hematopoiesis and dysplastic changes in the bone marrow, often leading to cytopenias
Clinical context
A 68-year-old man presents with fatigue and recurrent infections. His complete blood count shows pancytopenia with dysplastic changes on bone marrow biopsy. He has been experiencing frequent nosebleeds and bruising. His CBC reveals anemia, thrombocytopenia, and neutropenia with blasts in the bone marrow.
Mnemonic
Myelodysplasia = Myeloid dysfunction with Dysplastic changes leading to Cytopenias