renal tubular acidosis
Definition
A medical condition characterized by the kidney's inability to acidify urine, leading to metabolic acidosis
Clinical context
A 45-year-old woman presents with fatigue, muscle weakness, and kidney stones. Laboratory studies reveal elevated serum creatinine, low bicarbonate levels, and impaired urine acidification despite normal serum potassium. She has a history of recurrent urinary tract infections. The most likely diagnosis is renal tubular acidosis, a condition where the kidneys fail to acidify urine properly, resulting in chronic metabolic acidosis.
Mnemonic
RTA = Renal Tubular Acidosis - Remember: 'Tubular' = tube dysfunction, 'Acidosis' = acid buildup in blood, 'Renal' = kidney problem