Etymed
splenomegaly
Definition
pathological enlargement of the spleen
Clinical context
A 65-year-old man presents with left upper quadrant pain and early satiety. Physical examination reveals a large, firm spleen extending to the left of the midline. His CBC shows thrombocytopenia and anemia. Imaging confirms significant splenomegaly. What is the most likely underlying cause?
Mnemonic
Spleen enlarged = Splenomegaly - think 'splen' + 'megaly' = big spleen