Etymed

vasculitis

vas/o cul/o itis

Definition

inflammation of blood vessels or lymphatic vessels

Clinical context

A 45-year-old woman presents with fever, weight loss, and palpable purpura on her lower extremities. Laboratory studies reveal elevated inflammatory markers and positive anti-neutrophil cytoplasmic antibodies (ANCA). Biopsy of affected skin shows transmural inflammation of small and medium-sized arteries. This constellation of findings is consistent with vasculitis affecting the cutaneous vasculature.

Mnemonic

Vasculitis = Vascular inflammation causing vessel wall damage

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