virilization
Definition
The development of male characteristics in a female, or the appearance of male characteristics in a male
Clinical context
A 28-year-old women presents with hirsutism, acne, and progressive clitoromegaly. Physical examination reveals increased muscle mass and male pattern balding. Laboratory studies show elevated testosterone levels. What condition best explains these findings?
Mnemonic
VIRILIZATION = V = Virile (male), I = Increased muscle, R = Rapid growth, I = Increased libido, L = Lethargy, I = Increased irritability, Z = Zygote (fetal development)